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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Clin Immunol. 2012 Oct 18;33(2):10.1007/s10875-012-9817-6. doi: 10.1007/s10875-012-9817-6

Fig. 3. Patients with sarcoidosis exhibit an ESAT-6 specific Th-1/Th-17 response.

Fig. 3

a Representative plots of flow cytometric detection of production of intracellular IL-17A, surface expression of IL-23R and production of intracellular IFN-γ in CD4+ T cells from ESAT-6 stimulated PBMC of healthy controls and patients with sarcoidosis. b Frequencies of IL-17A+CD4+ and IL-23R+CD4+ from ESAT-6 stimulated PBMC of healthy controls (diamonds, n=9) and patients with sarcoidosis (squares, n=24). c Representative plots of flow cytometric detection of production of intracellular IFN-γ in CD4+ T cells from ESAT-6 stimulated PBMC of healthy controls and patients with sarcoidosis. d Frequencies of CD4+ T cells expressing IFN-γ from ESAT-6 stimulated PBMC of healthy controls (diamonds, n=9) and patients with sarcoidosis (squares, n=24). P values are indicated