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Osmolality of THC-HG in Cremophor RH 40, Poloxamer 188, Poloxamer 407, Polysorbate 80 and Tyloxapol in IPBS at 25 °C. Results are depicted as mean ± SD (n=3).
| Excipient | Concentration (% w/v) | Osmolality (mOsm) |
|---|---|---|
| Plain IPBS | - | 281.6 ± 1.7 |
|
| ||
| Cremophor RH 40 | 0.1 | 282.6 ± 0.5 |
|
| ||
| 0.25 | 284.3 ± 0.5 | |
|
| ||
| 0.5 | 292.3 ± 1.2 | |
|
| ||
| Poloxamer 188 | 0.1 | 282 ± 2.2 |
|
| ||
| Poloxamer 407 | 0.1 | 282.9 ± 1.2 |
|
| ||
| 0.16 | 283.6 ± 0.5 | |
|
| ||
| Polysorbate 80 | 0.1 | 282.6 ± 0.5 |
|
| ||
| Tyloxapol | 0.1 | 283 ± 0.8 |
