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The effect of TXYF on PAR-2 mRNA expression in the colonic mucosa of PI-IBS rats (n=10)
| Group | Dose (g/kg) | Relative expression quantification of PAR-2mRNA |
|---|---|---|
| Normal rats |
- |
0.634±0.224 |
| PI-IBS rats |
- |
1.485±0.537** |
| TXYF-H rats |
4.8 |
0.912±0.197# |
| TXYF-M rats |
2.4 |
1.104±0.285# |
| TXYF- L rats |
1.2 |
1.206±0.318 |
| Alosetron rats | 1.5×10-3 | 0.903±0.175# |
**p<0.01 vs Normal rats; #p<0.05 vs PI-IBS rats.
