Table 1.
|
pGag (titer) |
pGag + pTat (titer) |
Blank (titer) |
IgG1 (Th2) |
300 |
300 |
50 (negative) |
IgG2a (Th1) |
50 (negative) |
350 |
50 (negative) |
Th1:Th2 index |
0.17 |
1.17 |
-- |
|
pEnv (titer) |
pEnv + pTat (titer) |
Blank (titer) |
IgG1 (Th2) |
600 |
750 |
50 (negative) |
IgG2a (Th1) |
650 |
750 |
50 (negative) |
Th1:Th2 index |
1.08 |
1 |
-- |
|
pPol (titer) |
pPol + pTat (titer) |
Blank (titer) |
IgG1 (Th2) |
200 |
200 |
50 (negative) |
IgG2a (Th1) |
50 (negative) |
400 |
50 (negative) |
Th1:Th2 index | 0.25 | 2 | -- |
The mean value of each group of mice (the same data as showed in Figure 4B) was showed in this table, and used to calculate the index of IgG2a/IgG1 [26]. Th-polarization response in mice was determined according to the value of IgG2a/IgG1 [27,28]. The value of Th1:Th2 are accurate to two decimal places. All experiments were repeated once, and the results were consistent.