Table 4.
Comparison of four methods on aligning the PPI networks of KSHV and VZV
| Method | nEdge | nOrth | EC | OP | P-value |
|---|---|---|---|---|---|
| GRAAL | 45 | 2 | 39.1% | 12.5% | 2.6 × 10−19 |
| GraphAlignment | 51 | 9 | 44.3 % | 56.3% | 4.3 × 10−25 |
| IsoRank | 48 | 15 | 41.8% | 93.8% | 4.1 × 10−22 |
| BinAligner(S) | 68 | 0 | 59.1% | 0 | 6.2× 10−44 |
| BinAligner | 58 | 16 | 50.4% | 100% | 1.0 × 10−32 |
BinAligner(S) means pure graph structure alignment using BinAligner; nEdge denotes the number of aligned matched edges; nOrth denotes the number of aligned orthologous pairs; EC denotes edge correctness and OP denotes orthologous percentage.