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Receiver operating characteristic (ROC) curve for D0.5cc (dose to 0.5 ml of temporal lobe volume). The cutoff point for D0.5cc (as the temporal lobe dose tolerance) was determined as 69 Gy for NPC patients treated with IMRT. At a D0.5cc of 69 Gy, the sensitivity and specificity for the prediction of radiation-induced temporal lobe injuries (TLI) were 0.85 and 0.85, respectively.
