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. 2013 Oct 9;14(Suppl 14):S4. doi: 10.1186/1471-2105-14-S14-S4

Table 1.

Microarray vs. RNA-seq

Microarray RNA-seq
Principle Hybridization Cloning & sequencing

Required amount of RNA High Low

Resolution Several to 100 bp Single base

Distinguish Allelic expression? Limited Yes

Distinguish splice forms? Limited Yes

Discover new genes? No Yes

Strandedness? No Yes

Dynamic range Few hundred-fold > 8000-fold

Reproducibility Yes Yes

Cost Medium High (due to computation)
HHS Vulnerability Disclosure