Table 1.
Clinical characteristics of penicilliosis marneffei among patients with and without HIV infection
| Variables | HIV-infected patients (N = 116) | HIV-uninfected patients (N = 34) | p-values |
|---|---|---|---|
| Age (years) |
39 (32, 48.5) |
55 (50, 64) |
<0.001 |
| Female |
37 (31.9%) |
17 (50%) |
0.068 |
| Body weight (kilograms) |
49 (42, 57) |
48 (40, 52) |
0.172 |
| Underlying diseases* |
116 (100%) |
12 (35.3%) |
<0.001 |
| HIV |
116 (100%) |
0 (0) |
|
| Diabetes |
2 (1.7%) |
3 (8.8%) |
|
| Lymphoma |
0 |
2 (5.9%) |
|
| Colon cancer |
0 |
1 (2.9%) |
|
| Systemic lupus erythematosus |
0 |
6 (17.7%) |
|
| Mixed connective tissue disease |
0 |
1 (2.9%) |
|
| Myasthenia gravis |
0 |
1 (2.9%) |
|
| Receiving immunosuppressive drugs† |
0 |
6 (17.7%) |
<0.001 |
| Previous opportunistic infections or co-infections |
42 (36.2%) |
31 (91.2%) |
<0.001 |
|
Cryptococcus neoformans |
3 (7.1%) |
0 |
|
|
Mycobacterium tuberculosis |
23 (54.8%) |
3 (9.7%) |
|
|
Pneumocystis jiroveci |
12 (28.6%) |
0 |
|
| Non tuberculous mycobacteria |
2 (4.8%) |
15 (48.4%) |
|
| Cytomegalovirus |
5 (11.9%) |
0 |
|
| Herpes zoster virus |
7 (16.7%) |
0 |
|
|
Candida spp. |
2 (4.8%) |
0 |
|
|
Isospora belli |
1 (2.4%) |
0 |
|
|
Histoplasma capsulatum |
0 |
1 (3.2%) |
|
|
Salmonella spp. |
0 |
8 (25.8%) |
|
| Rhodococcus equi | 0 | 1 (3.2%) |
Data are presented in number (%) or median (IQR).
*One patient may have ≥1 underlying diseases.
†See text.