Table 3.
Laboratory findings of penicilliosis marneffei among patients with and without HIV infection
| Variables | HIV-infected patients (N = 116) | HIV-uninfected patients (N = 34) | p-values |
|---|---|---|---|
| Hemoglobin (g/dL) |
9.6 ± 2.1 |
9.7 ± 1.8 |
0.726 |
| White blood cells (× 103cells/ mm3) |
4.1 (3.0, 5.9) |
15.6 (10.1, 24.0) |
<0.001 |
| Platelet count (× 103 cells/mm3) |
119.5 (68.9, 218.0) |
390.0 (176.0, 508.0) |
<0.001 |
| Creatinine (mg/dL) |
0.9 (0.75, 1.2) |
1.1 (0.8, 1.4) |
0.168 |
| CD4 cell count (cells/mm3) |
14 (8, 40) |
640 (428, 833) |
<0.001 |
| (N = 105) |
(N = 16) |
||
| CD4% |
3 (1, 6) |
30 (28, 37) |
<0.001 |
| (N = 105) |
(N = 16) |
||
| ALT (U/L) |
43.5 (25.5, 69.5) |
17.5 (14, 34) |
<0.001 |
| Albumin (g/dL) |
2.5 (2.1, 3.2) |
2.3 (1.9, 2.7) |
0.164 |
| Positive cultures |
|
|
|
| Blood |
89/116 (76.7) |
16/34 (47.1) |
0.001 |
| Lymph node |
21/31 (67.7) |
7/13 (53.8) |
0.496 |
| BAL fluid |
1/4 (25.0 ) |
4/10 (40.0) |
1.000 |
| Bone marrow |
28/52 (53.8) |
3/8 (37.5) |
0.465 |
| Skin |
42/47 (89.4) |
11/14 (78.6) |
0.369 |
| Sputum |
3/32 (9.4) |
1/8 (12.5) |
1.000 |
| Chest roentgraphy |
N = 33 |
N = 16 |
|
| Normal |
9 (27.3%) |
1 (6.3%) |
0.135 |
| Abnormal |
|
|
|
| Interstitial infiltration |
10 (30.3%) |
0 |
|
| Alveolar infiltration |
7 (21.2%) |
7 (43.8%) |
|
| Pleural effusion |
4 (12.1%) |
7 (43.8%) |
|
| Interstitial and alveolar |
0 |
1 (6.3%) |
|
| Cavitary lesion | 3 (9.1%) | 0 |
Data are presented in number (%), median (IQR), or mean ± standard deviation.
Abbreviations: ALT Alanine aminotransferase, BAL Bronchoalveolar lavage.