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. 2013 Oct 2;8:227. doi: 10.1186/1748-717X-8-227

Table 7.

Incidence of IORN of the upper and lower jaw in the literature

Author group Year of publication Incidence Remarks
Ben-David et al. [13] (n = 176)
2007
0
Multiple tumour localizations
Primary treatment (no surgery)
IMRT
108/176 radiochemotherapy
Berger et al. [14]
2010
1-5%
Literature survey
Crombie et al. [15] (n = 54)
2012
36%
53/54 radiochemotherapy
Gomez et al. [16] (n = 168)
2011
1.2%
Multiple tumour localizations
IMRT
Gomez et al. [29] (n = 35)
2009
5%
IMRT
Jerecek-Fosså et al. [17]
2002
0.4-56%
Literature survey
Jham et al. [7] (n = 207)
2008
5.5%
Head and neck cancer
Katsura et al. [18] (n = 39)
2008
15%
 
Lee et al. [19] (n = 189)
2008
6.6%
Oral cavity and oropharynx
Monnier et al. [20] (n = 73)
2011
40%
Oral cavity and oropharynx
Oh et al. [21] (n = 81)
2004
4.9%
 
Reuther et al. [5] (n = 830)
2003
8.2%
Oral cavity and oropharynx
Stenson et al. [22] (n = 27)
2010
18.4%
Surgery, adjuvant radiochemotherapy
Storey et al. [23] (n = 83)
2001
6%
Malignant submandibular tumours
Studer et al. [24] (n = 304)
2011
Grade 2 EORTC: 1.6%
Oral cavity and oropharynx
Conventional dental care vs. risk-adapted dental care
IMRT
Thiel [25]
1989
4-35%
Literature survey
Thorn et al. [26] (n = 80)
2000
74%/3 years
Multiple tumour localizations
Tsai et al. [27] (n = 402)
2013
7.5%
Oropharyngeal cancer, median time to IORN 8 months
Turner et al. [28] (n = 333) 1996 5.9%