Table 2.
Statistical analysis of the occurrence of NBN p.I171V mutation in leukemia patients and controls
| Leukemia n=220 | Controls n=2400 | OR [95% CI] | p | |||||
|---|---|---|---|---|---|---|---|---|
|
Gene |
Mutation |
ALL |
AML |
|
ALL |
AML |
ALL |
AML |
|
NBN |
p.I171V |
5 |
2 |
12 |
5.437 (1.894 – 15.60) |
21.60 (4.631 – 100.7) |
0.00041 |
0.00011 |
| |
|
ALL+AML |
|
ALL+AML |
ALL+AML |
|||
| NBN | p.I171V | 7 | 12 | 6.540 (2.547 – 16.79) | 0.00011 | |||
1Result statistically significant (P<0.05), OR (95% CI) -Odds ratio (95% confidence interval).