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. 2013 Dec 4;8(12):e80861. doi: 10.1371/journal.pone.0080861

Figure 9. Single B cyclin-EGFP can rescue the G2 arrest of endogenous cyclin B1 and B2 co-depletion.

Figure 9

Two clonal cell lines for each B cyclin and two independent experiments were performed as in Figure 8. The percentage of 4C cells in control cells (Endo) were normalized to 1. Co-depletion increases G2 cells by 2 to 3 times (None). Expression of B cyclin-EGFP in the presence of endogenous cyclins did not change G2 fractions (Endo+Exo). Expression of single B cyclin-EGFP in the presence of endogenous cyclin co-depletion restored G2 fractions close to normal cycling levels (Exo).