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. 2013 Sep 27;10(4):342–355. doi: 10.1007/s11904-013-0176-6

Table 3.

Screen versus gold standard NP impairment rates and standard criterion validity indexes for studies where sensitivity and specificity is 70 % or higher (%)

Study Screen NP IR Screen IR Cut-off Sample Sensitivity Specificity Accuracy
[40] Morgan HDS 43a - T < 40 HAD only 93 73 -
[31] Moore 4 NP tests 19b - 4 tests T < 40, or Entire sample 87 87 -
2 tests T < 40 + 1 test T < 35, or
2 tests T < 35,
or 1 test T < 40 + 1 test T < 30,
or 1 test T < 25
[31] Moore 3 NP tests 19b - 3 tests T < 40 or Entire sample 87 76 -
1 testT < 40 + 1 test T < 35, or
1 test T < 30
[25] Cysique CogState 62a 62a - Entire sample 81 70 -
[23] Carey NP tests (HVLT-R & ndGP) 29a 34a T < 40 on 1 test or T < 35 on 2 tests Entire sample 78 85 83
[40] Morgan HDS 43a - T < 40 MND only 77 73 -
[23] Carey NP tests (HVLT-R & Cod) 29a - T < 40 on 1 test or T < 35 on 2 tests Entire sample 75 92 87
[31] Moore 2 NP tests 19b - 2 tests T < 40 or Entire sample 73 83 -
1 test T ≤ 35
[29] Sacktor (American) IHDS 38a - ≤10.5 Entire sample 71 79 -
[21] Becker CAMCI 31a 30b - Entire samplec 72 98 -

Consideration of the sample in question is necessary for proper screen selection. See reference list for numbered studies. Rounded to nearest whole value. Ordered with balance of highest sensitivity and specificity. NP = neuropsychological. IR = Impairment rate. Accuracy = overall correct classification accuracy. ‘-‘ = not reported. Sensitivity refers to the proportion of individuals identified as impaired on both the gold standard and the screen. Specificity refers to the proportion of individuals identified as unimpaired on both the gold standard and the screen. HAD = HIV Associated Dementia. MND = Mild Neurocognitive Disorder. HVLR-R = Hopkins Verbal Learning Test, revised. ndGP = nondominant hand Grooved Pegboard. Cod = Coding. a manually calculated; b values reported; c sample excluded ANI category