Table 1.
Description of AMD phenotypic subtypes according to Newman et al. [1]. Abbreviated names in the first column are used in labeling the cladograms' legends in Figures 1 and 2.
| AMD phenotype | Alternative name | Description |
|---|---|---|
| MD1 | Pre-AMD | Hard macular drusen (<63 μm) only |
|
| ||
| MD2 | Subclinical pre-AMD |
Soft, distinct macular drusen (>63 μm) Macular pigmentary irregularities without soft drusen |
|
| ||
| Dry AMD | Dry AMD (non-GA) |
Soft, indistinct (>125 μm) or reticular macular drusen Soft distinct macular drusen (>63 μm) with pigmentary changes Soft indistinct macular drusen with pigmentary changes |
|
| ||
| GA | Geographic atrophy | Sharply demarcated area of apparent absence of the RPE (>175 μm) involving central macular region |
|
| ||
| CNV | Wet AMD | Subretinal choroidal neovascularization |
|
| ||
| GA/CNV | Geographic atrophy with choroidal neovascularization | |