Table 3.

Few examples revealing differences in the expression profiles based on selection of the most abundant isomiR versus the reference miRNA

3A)
miRNAs	Normal 1		Normal 2
	Reference miRNA frequency	Most abundant isomiR frequency	Reference miRNA frequency	Most abundant isomiR frequency
hsa-miR-10a-5p	171	935	195	792
hsa-miR-15b-5p	2266	4355	992	2547
hsa-miR-21-5p	30955	49979	33091	50565
hsa-miR-23a-3p	11160	21009	8375	17718
hsa-miR-26b-5p	3409	28934	3685	23018
hsa-miR-30d-5p	1449	14156	1893	15233
3B)
miRNAs	Patient 1		Patient 2
	Reference miRNA frequency	Most abundant isomiR frequency	Reference miRNA frequency	Most abundant isomiR frequency
hsa-miR-10a-5p	56	256	99	396
hsa-miR-15b-5p	1835	2342	1187	4114
hsa-miR-21-5p	8868	18032	36712	75907
hsa-miR-23a-3p	5793	11774	8296	16159
hsa-miR-26b-5p	2239	12346	10093	51801
hsa-miR-30d-5p	1638	8012	1619	15705

A) in Normal samples. (B) in Patient samples.