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. 2013 Dec 5;4:271. doi: 10.3389/fgene.2013.00271

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Copyright © 2013 Kikuchi, Tsuji, Yagi, Matsusaka, Tsuji, Kurebayashi, Ogawa, Aburatani and Kaneda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative data obtained from MALDI-TOF-MS imaging for three cancer samples. Cancer samples #1, #4, and #5 correspond to papillary cancer samples #1, #4, and #5 in Figure 3. First column: photomicrograph of a tumor section with hematoxylin/eosin (H/E) staining. Second, third, and fourth columns: MALDI-TOF-MS profile with detection of BRAF/RAS mutations. X-axis indicates mass-to-charge ratio (m/z) to distinguish wild-type and mutant allele, and Y-axis indicates signal intensity.