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. 2013 Sep 11;33(12):1955–1966. doi: 10.1038/jcbfm.2013.155

Figure 6.

Figure 6

Differences between wild-type (WT) and interleukin-10 knockout (IL-10 KO) mice in the brain inflammatory response are attenuated at day 7. Brain expression of most cytokine and chemokine mRNA is no longer significantly different between IL-10 KO and WT mice at day 7. n=6 mice per group. Values are expressed as fold versus control WT. *P<0.05, **P<0.01, ***P<0.001. TNF-α, tumor necrosis factor-α; TLR, Toll-like receptor; ICAM-1, intercellular adhesion molecule-1; MIP-1α, macrophage inflammatory protein-1α; IGF-1, insulin growth factor-1; MMP, matrix metalloproteinase; MCP-1, monocyte chemoattractant protein-1; TGF-β, transforming growth factor-β; Cox-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase.