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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cancer Res. 2013 Aug 23;73(23):10.1158/0008-5472.CAN-13-1550. doi: 10.1158/0008-5472.CAN-13-1550

Figure 3. PD-1 or PD-L1 blockade causes regression of ID8 tumor.

Figure 3

Mice were inoculated i.p. with 5 × 106 ID8 tumor cells (n=12). These mice were injected either therapeutically (starting at 30 days after tumor inoculation) or prophylactically (starting at 20 days after tumor inoculation) 5 times i.p. with αPD-1 (200ug), αPD-L1 (200ug), or αPD-L2 (200ug) blocking antibodies on alternate days either alone or in combination as indicated. The scheme and survival of therapeutic (i) and prophylactic models (ii) are shown. Results are from one of the 3 representative experiments.