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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Cancer Res. 2013 Aug 23;73(23):10.1158/0008-5472.CAN-13-1550. doi: 10.1158/0008-5472.CAN-13-1550

Figure 5. Synergistic effect of PD-1 blockade, GVAX or FVAX vaccination, and α4-1BB costimulation on ovarian ID8 tumor rejection.

Figure 5

(a) Three weeks after ID8 tumor inoculation, the mice were given i.p with 2 × 106 irradiated (150Gy) GVAX (top) or FVAX (bottom) once. A week later mice were injected 5 times i.p. with αPD-1 (200ug), αPD-L1 (200ug), αPD-L2 (200ug) on alternate days or a single dose 200ug of α-4-1BB either alone or in combination as indicated. Results are from one of the 3 experiments.