Table 2.
Multivariable unconditional logistic regression models of the effects of regular oral antihistamine use on glioma risk, both in the overall HCCCSa study population and stratified by self-reported history of allergies/asthma.
Logistic regressionb | |||
---|---|---|---|
Odds Ratios (95% CI)c | |||
Overall | Allergies/Asthma | ||
(n=824) | Yes (n=215) | No (n=609) | |
Regular Antihistamine Use | |||
Yes | 2.15 (1.42–3.25) | 4.19 (2.06–8.51) | 1.59 (0.95–2.67) |
No | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Self-Reported Allergies/Asthma | |||
Yes | 0.28 (0.20–0.41) | - | - |
No | 1.00 (reference) | - | - |
Self-Reported History of Chickenpox | |||
Yes | 0.49 (0.34–0.71) | 1.81 (0.58–5.70) | 0.39 (0.26–0.60) |
No | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
IgE Levels | |||
≥250IU per mL | 1.45 (0.77–2.74) | 1.76 (0.53–5.84) | 1.45 (0.68–3.13) |
<250 IU per mL | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Note. IU per mL= International Units per milliliter
Harris County Case-Control Study
All odds ratios are also adjusted for matching variables (age, sex, and race).
Bolding indicates statistical significance.