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. 2013 Oct 9;13:45. doi: 10.1186/1472-6823-13-45

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Copyright © 2013 Nakashima et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histology of the pituitary lesion. A. Hematoxylin-Eosin (HE) stain (×100). The pituitary gland is completely replaced by abnormal lymphocytes. B. HE stain (×400). The sections show diffuse proliferation of large-sized abnormal lymphoid cells. C. CD20 immunostaining (×400). These atypical cells are positive for CD20. D. CD3 immunostaining (×400). These atypical cells are negative for CD3.