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. 2013 Dec 5;4:426. doi: 10.3389/fimmu.2013.00426

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Copyright © 2013 Alagha and Zaikin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Linear form of external signals in GATA1-PU.1 genetic switch. (A) Two external signals S₁ and S₂ with different rising times but equal steady states at S_max = 10. (B) The difference between the external signals with maximal asymmetry at A.