Table 1.
Relationship between p-AKT expression and ALK activation in ALCL
|
p-AKT + (n = 54) |
p-AKT- (n = 17) |
p-value | |||
|---|---|---|---|---|---|
| No. of patients | % | No. of patients | % | ||
| ALCL (n = 71) |
|
|
|
|
|
| ALK+ |
38 of 54 |
70 |
6 of 17 |
35 |
|
| ALK- |
16 of 54 |
30 |
11 of 17 |
65 |
0.009* |
| ALK + (n = 44) |
|
|
|
|
|
| ALK (n + c) |
29 of 39 |
74 |
4 of 5 |
80 |
|
| ALK (c) | 10 of 39 | 26 | 1 of 5 | 20 | 0.779 |
* Statistically significant value.
ALK(n + c) indicates ALK + with both nucleus and cytoplasmic staining; ALK(c), ALK + with cytoplasmic staining only.