Table 1.
Baseline characteristics of CAD patients and controls
| Variable | CAD patients ( n = 151) | Controls ( n = 34) | Pvalue |
|---|---|---|---|
| Age (years) |
57 ± 11 |
56 ± 12 |
0.6 |
| Body-mass index (kg/m2) |
27.5 ± 3.8 |
27.3 ± 3.7 |
0.8 |
| Current smokers, n (%) |
41 (27%) |
7 (21%) |
0.5 |
| Left ventricular ejection fraction (%) |
69 ± 7 |
70 ± 6 |
0.4 |
| Hypertension, n (%) |
121 (80%) |
25 (74%) |
0.4 |
| Systolic blood pressure (mm Hg) |
130 ± 10 |
129 ± 12 |
0.6 |
| Diastolic blood pressure (mm Hg) |
79 ± 8 |
80 ± 9 |
0.5 |
| Estimated GFR (mL/min per 1.73 m2) |
71 ± 10 |
75 ± 13 |
0.05 |
| Low-density lipoproteins cholesterol (mmol/L) |
2.8 ± 0.7 |
2.6 ± 0.7 |
0.3 |
| High-density lipoproteins cholesterol (mmol/L) |
0.9 ± 0.3 |
1.0 ± 0.4 |
0.02 |
| Triglycerides (mmol/L) |
1.5 ± 0.8 |
1.4 ± 0.7 |
0.5 |
| High-sensitivity C-reactive protein (mg/L) |
1.8 (1.1–3.8) |
1.6 (1.0–3.3) |
0.07 |
| Glucose (mmol/L) |
5.8 ± 0.8 |
5.6 ± 0.7 |
0.25 |
| HOMA-IR index |
3.2 (2.4–4.9) |
2.9 (2.3–4.7) |
0.2 |
| ADMA (μmol/L) |
0.51 ± 0.10 |
0.46 ± 0.09 |
0.01 |
| L-arginine (μmol/L) | 70 ± 18 | 71 ± 17 | 0.7 |
Data are shown as mean ± SD, median (interquartile range) or n (%).
Abbreviations:ADMA asymmetric dimethylarginine, CAD coronary artery disease, GFR glomerular filtration rate, HOMA-IR homeostasis model assessment for insulin resistance.