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The decline in FEV1 (l) for a 41 year-old male. Footnote: Between 1980 and 1985 a severe drop in FEV1 from 2.7 to 1.7 liters was noted. Started with augmentation therapy in 1985, the lung function parameters stabilised over a period of approximately 3 years. The number of severe pulmonary infections requiring hospitalisation increased from 1989 and were accompanied by a rapid decrease in FEV1. Published from reference 46 with permission from S. Karger AG Basel.
