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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Am J Reprod Immunol. 2013 Dec;70(6):10.1111/aji.12171. doi: 10.1111/aji.12171

Fig. 2. Resolution of C. muridarum infection and the development of oviduct pathology are not influenced by the absence of IL-22.

Fig. 2

(A) The kinetics of lower genital tract infection for C57BL/6 (black squares) and IL-22 KO mice (open circles, dashed line) does not differ (P > 0.05 via two-way repeated measures ANOVA). Data points represent the mean ± SEM of IFU values from 6 mice per strain from a single representative experiment of two. (B,C) Histological analysis of oviduct epithelial cell erosion (B) and oviduct dilatation (C) in genital tracts harvested on day 42 post-infection revealed no difference between the strains. (P > 0.05 via Mann-Whitney U-test). Data points represent semi-quantitative scoring of oviduct pathology for individual mice with 6 mice per strain from a single experiment of two. C57BL/6 (black squares) and IL-22 KO mice (open circles). Median indicated by horizontal line.