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MDR cell lines. MDR1-Pgp expression was determined by the highly specific mAb MM4.17. In Panel A, the binding profiles obtained by staining the parental drug sensitive cell line CCRF-CEM and its derivative MDR variants (CEM-VBL10 and CEM-VBL100) are shown. In Panel B, there are the binding profiles of the AML drug sensitive/resistant cell pairs HL60 and HL60-DNR.
