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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Blood Cells Mol Dis. 2013 Aug 28;52(1):35–45. doi: 10.1016/j.bcmd.2013.07.016

Figure 5.

Figure 5

Examples of homozygous VHLR200W-induced genes that were modulated by iron deficiency. Four genes, BCL2L1 (A), CA1 (B), CXCL16 (C) and RELT (D), were induced in VHLR200W homozygotes (left panels), where their expression level was correlated with serum ferritin concentration (right panels). Left panel shows 17 WT individual and 8 VHLR200W homozygotes matched for iron status; right panel shows 24 VHLR200W homozygotes. Black points denote WT individuals and red points denote VHLR200W homozygotes. P-values in right panels denote Spearman's rank test for correlation between gene expression level and log (ferritin) in VHLR200W homozygotes.