Table 2.
Genes showing at least a 1.5-fold change in regulation in VHLR200W homozygotes.
| Direction | Affy ID | Gene Symbol | Gene Title | Fold |
|---|---|---|---|---|
| up regulation | 3142967 | CA1 | carbonic anhydrase I | 2.8 |
| 2435005 | SELENBP1 | selenium binding protein 1 | 2.3 | |
| 2571510 | IL1B | interleukin 1, beta | 2.2 | |
| 3759006 | SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 2.1 | |
| 3360401 | HBB | hemoglobin, beta | 2.0 | |
| 3657253 | AHSP | alpha hemoglobin stabilizing protein | 2.0 | |
| 3444252 | CSDA | cold shock domain protein A | 2.0 | |
| 2343473 | IFI44L | interferon-induced protein 44-like | 1.9 | |
| 3257204 | IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 1.8 | |
| 3203855 | DCAF12 | DDB1 and CUL4 associated factor 12 | 1.8 | |
| 3090006 | SLC25A37 | solute carrier family 25, member 37 | 1.7 | |
| 3025500 | BPGM | 2,3-bisphosphoglycerate mutase | 1.7 | |
| 3257246 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 1.7 | |
| 3360417 | HBD | hemoglobin, delta | 1.7 | |
| 2777714 | SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 1.7 | |
| 3090053 | SLC25A37 | solute carrier family 25, member 37 | 1.7 | |
| 3902489 | BCL2L1 | BCL2-like 1 | 1.7 | |
| 3770345 | CD300E | CD300e molecule | 1.6 | |
| 2772566 | IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 1.6 | |
| 3621029 | EPB42 | erythrocyte membrane protein band 4.2 | 1.6 | |
| 2353988 | FAM46C | family with sequence similarity 46, member C | 1.6 | |
| 3809621 | FECH | ferrochelatase | 1.6 | |
| 3945515 | APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | 1.6 | |
| 3464860 | DUSP6 | dual specificity phosphatase 6 | 1.6 | |
| 3549575 | IFI27 | interferon, alpha-inducible protein 27 | 1.6 | |
| 2731513 | EREG | epiregulin | 1.6 | |
| 2775390 | MOP-1 | MOP-1 | 1.5 | |
| 3922100 | MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 1.5 | |
| 2896545 | GMPR | guanosine monophosphate reductase | 1.5 | |
| 3942531 | OSBP2 | oxysterol binding protein 2 | 1.5 | |
| 2773434 | CXCL2 | chemokine (C-X-C motif) ligand 2 | 1.5 | |
| down regulation | 2496536 | RPL31 | ribosomal protein L31 | 1.8 |
| 3031517 | GIMAP7 | GTPase, IMAP family member 7 | 1.8 | |
| 3617458 | GOLGA8A /8B | golgin A8 family, member A / member B | 1.7 | |
| 2781138 | LEF1 | lymphoid enhancer-binding factor 1 | 1.7 | |
| 2806468 | IL7R | interleukin 7 receptor | 1.6 | |
| 2821347 | ERAP2 | endoplasmic reticulum aminopeptidase 2 | 1.6 | |
| 2665199 | SATB1 | SATB homeobox 1 | 1.5 | |
| 2809793 | GZMK | granzyme K (granzyme 3; tryptase II) | 1.5 | |
| 2515627 | ITGA6 | integrin, alpha 6 | 1.5 | |
| 2837232 | ITK | IL2-inducible T-cell kinase | 1.5 | |
| 2823880 | CAMK4 | calcium/calmodulin-dependent protein kinase IV | 1.5 |