Table 2.
Description of the selected gene features between short-term and long-term survival group in GBM
| Gene | Region | Function | Up/down | AUC_diff |
|---|---|---|---|---|
| RAGE | 14q32.31 | Renal tumor antigen/threonine kinase activity/transferase activity | Up | 0.028 |
| ATAD3A | 1p36.33 | ATP binding/nucleotide binding | Down | 0.024 |
| HEMK1 | 3p21.31 | DNA binding/N-methyltransferase activity | Up | 0.012 |
| KMO | 1q43 | Integral to membrane/kynurenine 3-monooxygenase activity | Up | 0.012 |
| RBKS | 2p23.2 | D-ribose metabolic process/ribokinase activity | Up | 0.012 |
| CCNJL | 5q33.3 | Nucleus/regulation of progression through cell cycle | Down | 0.008 |
| LGALS8 | 1q43 | Extracellular space/sugar binding | Up | 0.008 |
| UPP1 | 7p12.3 | Cytoplasm/nucleoside metabolic process/nucleotide catabolic process | Up | 0.008 |
| BDH1 | 3q29 | 3-hydroxybutyrate dehydrogenase activity/metabolic process/mitochondrial inner membrane/mitochondrial matrix | Up | 0.004 |
| HFE | 6p22.1 | Antigen processing and presentation/ immune response/ protein complex assembly | Up | 0.004 |
| TUSC2 | 3p21.31 | Cell cycle/cell proliferation/cell-cell signalling/negative regulation of progression through cell cycle | Up | 0.000 |
The gene lists in the first column were sorted by the AUC_diff, which calculated the difference between the original AUC with 11 gene features and the AUC without one gene among 11 gene features.