Table 2.
Type of test | TP | FP | FN | TOP1 | TOP2 |
Qβ |
Cβ | |
(A) | Self-consistency | 205 | 3 | 9 | 9 | 11 | 88.1% | 0.824 |
Jacknife | 203 | 13 | 11 | 8 | 10 | 84.2% | 0.720 | |
(B) | Self-consistency | 206 | 2 | 8 | 10 | 11 | 66.9% | 0.604 |
Jacknife | 204 | 12 | 10 | 9 | 10 | 65.7% | 0.532 |
(A): Comparison against the manual annotation of the TM-segments. (B): comparison against the observed strands of PDB [29]. TP: True Positives. FP: False Positives. FN: False Negatives. TOP1: Proteins with correctly predicted topologies (strand localization and orientation of the loops). TOP2: Proteins with correctly predicted topologies, with the inclusion of shifted strand predictions. Qβ: Percentage of correctly predicted residues [36]. Cβ: Matthews Correlation Coefficient [36].