Table 1.
Results of hormone studies
| Hormone | Concentration | Reference |
|---|---|---|
| Basal hormones |
|
|
| 08:00 AM Serum Cortisol (μg/dl) |
40.75 |
5–25 |
| 22:00 PM Serum Cortisol (μg/dl) |
37.28 |
<5 |
| 08:00 AM ACTH (pg/dl) |
<5 |
<46 |
| 22:00 PM ACTH (pg/dl) |
<5 |
<46 |
| Urinary free cortisol (μg/day) |
2584 |
20–80 |
| Plasma renin activity (pg/ml) |
14.81 |
3–33 |
| Plasma aldosterone (pg/ml) |
270 |
10–310 |
| Urinary VMA (mg/day) |
3.9 |
1.0–7.0 |
| Serum DHEA-S (μmol/l) |
2.47 |
2.49–13.9 |
| High-dose dexamethasone testa |
|
|
| Serum cortisol (μg/dl) |
59.85 |
<46 |
| Urinary free cortisol (μg/day) | 4380 | 20–80 |
ACTH, adrenocorticotrophic hormone; VMA, vanillylmandelic acid; DHEA-S, dehydroepiandrosterone sulfate.
aDexamethasone (2 mg) was taken orally every 6 h at 9 AM, 3 PM, 9 PM and 3 AM for a total of eight doses. Blood was drawn 4 h after the last dose and 24 h urine was collected for measurement of the urine free cortisol level from 9 AM on the second day to 9 AM on the third day of dexamethasone administration.