Table 1.
Association of NRP-1 expression with clinicopathologic parameters of nasopharyngeal carcinoma patients
| Parameters | N |
NRP-1 expression (n, %) |
P | |
|---|---|---|---|---|
| High | Low | |||
|
Age | ||||
| < 48 |
100 |
63 (63.00) |
37 (37.00) |
NS |
| ≥ 48 |
166 |
113 (68.07) |
53 (31.93) |
|
|
Gender | ||||
| Male |
166 |
106 (63.86) |
60 (36.14) |
NS |
| Female |
100 |
70 (70.00) |
30 (30.00) |
|
|
Clinical stage | ||||
| I ~ II |
68 |
30 (44.12) |
38 (55.88) |
0.02 |
| III ~ IV |
198 |
146 (73.74) |
52 (27.26) |
|
|
T-stage | ||||
| T1 ~ T2 |
90 |
55 (61.11) |
35 (38.89) |
NS |
| T3 ~ T4 |
176 |
121 (68.75) |
55 (31.25) |
|
|
N-stage | ||||
| N0 |
78 |
50 (64.10) |
28 (35.90) |
NS |
| N1 ~ N3 |
188 |
126 (67.02) |
62 (32.98) |
|
|
WHO histological type | ||||
| II |
76 |
50 (65.79) |
26 (34.21) |
NS |
| III |
190 |
136 (71.58) |
54 (28.42) |
|
|
Recurrence | ||||
| No |
196 |
116 (59.18) |
80 (40.92) |
0.001 |
| Yes |
70 |
60 (85.71) |
10 (14.29) |
|
|
Metastasis | ||||
| No |
211 |
128 (60.66) |
63 (39.34) |
0.001 |
| Yes | 55 | 48 (87.27) | 7 (12.73) | |
‘NS’ refers to the difference without statistical significance.