Table 2.
Logistic Regression Analysis of CAT Single Nucleotide Polymorphisms with Obesity Under the Additive Model of Inheritance
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Obese |
Normal-weight |
|
MAF |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP ID | Usual designation | Allele 1/Allele 2 | 11 | 12 | 22 | 11 | 12 | 22 | Risk allele | Obese | Normal-weight | HW p | OR (95% CI) | p |
rs564250 | G/A | 117 | 53 | 7 | 117 | 59 | 5 | A | 0.299 | 0.326 | 0.864 | 1.00 (0.68, 1.46) | 0.987 | |
rs769214 | −844A/G | A/G | 65 | 89 | 23 | 84 | 81 | 16 | G | 0.503 | 0.448 | 0.414 | 1.42 (1.03, 1.96) | 0.035 |
rs7943316 | −89T/A | T/A | 65 | 89 | 23 | 82 | 83 | 16 | A | 0.503 | 0.459 | 0.298 | 1.38 (1.00, 1.91) | 0.050 |
rs1049982 | −20C/T | C/T | 65 | 89 | 23 | 83 | 81 | 16 | T | 0.503 | 0.450 | 0.414 | 1.41 (1.02, 1.95) | 0.039 |
rs525938 | A/G | 73 | 84 | 20 | 86 | 81 | 14 | G | 0.475 | 0.448 | 0.400 | 1.29 (0.93, 1.79) | 0.127 | |
rs494024 | G/A | 87 | 70 | 20 | 68 | 89 | 24 | A | 0.396 | 0.492 | 0.727 | 0.73 (0.54, 1.00) | 0.051 | |
rs769218 | G/A | 86 | 77 | 14 | 102 | 68 | 11 | A | 0.435 | 0.376 | 0.790 | 1.30 (0.93, 1.83) | 0.126 | |
rs12269988 | A/G | 166 | 11 | 0 | 167 | 14 | 0 | G | 0.062 | 0.077 | 1.000 | 0.77 (0.34, 1.77) | 0.542 | |
rs2073058 | A/G | 85 | 78 | 14 | 91 | 79 | 11 | G | 0.441 | 0.437 | 0.354 | 1.11 (0.80, 1.56) | 0.529 | |
rs4755374 | A/C | 132 | 43 | 2 | 137 | 41 | 3 | C | 0.243 | 0.227 | 0.816 | 1.03 (0.66, 1.61) | 0.892 | |
rs12803540 | A/G | 124 | 46 | 5 | 139 | 36 | 4 | G | 0.263 | 0.201 | 0.381 | 1.35 (0.89, 2.07) | 0.160 | |
rs7104301 | +33078A/G | A/G | 84 | 79 | 14 | 91 | 79 | 11 | G | 0.446 | 0.437 | 0.202 | 1.13 (0.81, 1.59) | 0.467 |
Values of the statistically significant associations are shown in bold.
Allele 1/2, major/minor allele; CI, confidence interval; HW, Hardy–Weinberg; MAF, minor allele frequency; OR, odds ratio (adjusted for sex and age); p, p-value of the logistic regression analysis; SNP, single nucleotide polymorphism.