Table 3. Results obtained by binomial sampling with various recombination fractions.
T | L | Δta | rb | Neutral (s0 = 0) | Selective (s0 = 0.05) | ||
---|---|---|---|---|---|---|---|
Binomialc | Pseudod | Binomialc | Pseudod | ||||
[Model 1′]e | |||||||
10 | 2 | 5 | Free | 5.19 | 5.06 | 20.45 | 21.05 |
0.1 | 4.66 | − | 19.90 | − | |||
0.01 | 4.97 | − | 19.33 | − | |||
0 | 5.14 | − | 19.85 | − | |||
20 | 5 | 5 | Free | 5.00 | 4.94 | 36.06 | 36.48 |
0.1 | 4.97 | − | 36.05 | − | |||
0.01 | 4.95 | − | 37.08 | − | |||
0 | 4.84 | − | 35.76 | − | |||
[Model 5′]f | |||||||
5 | 1 | 5 | Free | 5.07 | 5.01 | 8.57 | 8.34 |
0.1 | 4.93 | − | 8.80 | − | |||
0.01 | 5.08 | − | 8.09 | − | |||
0 | 5.41 | − | 8.13 | − | |||
10 | 5 | 2 | Free | 4.59 | 4.99 | 64.32 | 65.73 |
0.1 | 5.27 | − | 64.23 | − | |||
0.01 | 4.80 | − | 62.55 | − | |||
0 | 4.98 | − | 63.21 | − |
Values indicate the rejection rates (%) obtained by 10,000 simulations for binomial sampling or by 100,000 simulations for pseudo-sampling under a nominal significance level of 5%.
The number of reference were R = 10 The initial frequencies for all R + 1 loci, xh,0, are assumed to be 0.5.
.
r, recombination fraction per generation between two adjacent loci of R + 1 loci. “Free” refers to free recombination.
Binomial, the binomial sampling.
Pseudo, the pseudo-sampling method used in this study.
Model 1′, the constant-size model with N = 100.
Model 5′, the severe bottleneck model with N(t) reduced to 1/200 of that in Model 5.