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. 2013 Oct 18;3(12):2173–2185. doi: 10.1534/g3.113.007674

Table 2. Validated DLBCL subtype signature genes.

Gene Name Gene Description GCB Read Counts ABC Read Counts Fold Change FDR
ABC signature
 BCL2 B-cell CLL/lymphoma 2 4,599.52 22,162.49 4.82 4.90E-05
 CCND2 Cyclin D2 31.20 3692.67 118.60 1.56E-18
 CFLAR CASP8 and FADD-like apoptosis regulator 460.63 6463.37 14.03 5.52E-09
 FOXP1 forkhead box P1 1202.37 6588.56 5.46 1.13E-04
 IRF4 Interferon regulatory factor 4 976.01 21,475.28 22.01 2.43E-14
 NFKBIZ Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 962.34 8119.55 8.46 5.63E-06
GCB signature
 BCL6 B-cell CLL/lymphoma 6 15,105.68 5124.25 0.34 1.94E-02
 MAPK10 Mitogen-activated protein kinase 10 1473.10 57.42 0.04 4.45E-05
 MME (CD10) Membrane metallo-endopeptidase 6163.64 663.16 0.11 6.01E-05
 MYBL1 v-myb myeloblastosis viral oncogene homolog (avian)-like 1 2932.21 661.39 0.23 4.99E-02

DLBCL, diffuse large B-cell lymphoma; GCB, germinal center B-cell-like; ABC, activated B-cell-like; FDR, false-discovery rate; CLL, chronic lymphocytic leukemia.