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. Author manuscript; available in PMC: 2013 Dec 5.
Published in final edited form as: J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2013;31(4):10.1080/10590501.2013.844755. doi: 10.1080/10590501.2013.844755

Figure 3.

Figure 3

The potential interplay among androgen, estrogen and the liver, which may be mainly responsible for the gender disparity in BC risk. The illustration shows the potential opposing effects of androgen and estrogen on liver handling of aromatic amines and on carcinogenesis in the bladder.