Table 2.

Helicobacter pylori ferric uptake regulator-regulated genes that have been shown to play a role in colonization.

Gene name	Function	Animal model of infection	Ref.
feoB	Iron transport	Mouse	[27]
fec A1	Iron transport	Gerbil	[105]
pfr	Iron storage	Gerbil	[106]
pdxJ	Vitamin B6 biosynthesis	Mouse	[107]
putA	Proline metabolism	Mouse	[101]
ggt	Synthesis and degradation of glutathione	Mouse/piglet	[108,109]
faB†	Motility	Piglet	[110]
sodB	Oxidative stress defense	Mouse	[111]
hydABCDE	Hydrogenase	Mouse	[112]
cagA‡	Cytotoxicity	Gerbil	[76]
nikR	Nickel homeostasis	Mouse	[50]

^†Colonization of a double flaA/flaB mutant was analyzed.

^‡Mongolian gerbils were maintained on an iron-deficient diet.