TABLE 1.

Review of published reports on Aerococcus viridans endocarditis

Case	Age, years/sex	Clinical presentation	Diagnosis	Treatment	Complications	Resistant	Ref
1	49/M	Subacute (7 months): Fever; polymyalgia; mild AR murmur	14×15 mm AV veg on TEE	Ampicillin/amikacin	AV thickening/mild AR. Medical Rx. No relapse at 18 months	Quinolones/aminoglycosides	40
2	62/M	Subacute (1 month): Fever; weight loss; dyspnea/MR murmur; Janeway lesion; splenomegaly	13×12 mm veg on anterior mitral leaflet	Ceftriaxone/amikacin	Splenectomy for splenic abscesses. MVR. No relapse at 12 months	Quinolones	40
3	40/M	Subacute (3 weeks): Fever/fatigue; arthralgias; Osler nodes	14×11 mm veg at aortic cusp on TEE	Penicillin G/gentamicin	Medical Rx. No relapse at 38 months		40
4	45/F	Acute (3 days): Fever; dyspnea; ataxia; Janeway lesion; MR murmur; CHF	7×6 mm veg on anterior leaflet and posterior leaflet 5×3 mm	Penicillin G/gentamicin	MVR		40
5	10/M	Subacute (1 month): Fever; dyspnea; arthralgia; hematuria; clubbing; MR murmur; CHF	Veg on mitral leaflet	Norfloxacin/amikacin	Compensated MR. Medical Rx	Penicillin/ampicillin/cefotaxime/gentamicin	41
6	28/M	Subacute (6 months): Fever; rheumatic complaints; hematuria; AR murmur	Flail aortic leaflet with veg	Penicillin G/gentamicin	AoVR. No relapse at 6 months		44
7	44/M	Acute (few days): Fever; hematuria; splenomegaly; AR murmur	Not reported	Penicillin/streptomycin	CHF 6 weeks post discharge. Sudden death		42
8	54/M	Subacute (4 months): Fever; back pain; systolic murmur	Billowing leaflet	Penicillin	Medical Rx. No relapse at 10 weeks	Sulfonamide	43
9	58/M	Acute (4 days): Fever; pyuria/hematuria; altered LOC; diastolic murmur	10 mm veg on noncoronary cusp of AV on TEE	Cefotaxime/vancomycin	Medical Rx. Well at 3 months outpatient follow-up	Chloramphenicol/clindamycin/erythromycin/gentamicin/TMP-SMX	39
10	44/F	Subacute (2 weeks): Fever; AF; systolic murmur at AV area	Rheumatic AV and MV; moderate MS; oscillating mass 11×10 mm, MG 35 mmHg across AV on TEE	Ampicillin/sulbactam/gentamicin	Enlarging veg (21×10 mm) causing AV obstruction s/p 3 weeks of oral antibiotics requiring AoVR/MVR		38

AF Atrial fibrillation AoVR Aortic valve replacement; AR Aortic regurgitation; AV Aortic valve; CHF Congestive heart failure; F Female; LOC Level of consciousness; M Male; MG Mean gradient; MR Mitral regurgitation; MS Mitral stenosis; MV Mitral valve; MVR Mitral valve replacement; Ref Reference; Rx Treatment; s/p Status post; TEE Transesophageal echocardiogram; TMP-SMX Trimethoprim-sulfamethoxazole; Veg Vegetation