Table 6.
Group | TC | TC | TC | TC | TAG | TAG | TAG | TAG | VLDL | VLDL | LDL | LDL | HDL | HDL | LDL/HDL | LDL/HDL |
D1 | D14 | D21 | D29 | D1 | D14 | D21 | D29 | D14 | D29 | D14 | D29 | D14 | D29 | D14 | D29 | |
Gl (2.5%) | 2.47a | 3.21bc | 2.81 | 2.58 | 0.53 | 0.57 | 0.80 | 0.69 | 0.07 | 0.09 | 1.45c | 1.08 | 1.69c | 1.42 | 0.88 | 0.79 |
Lovastatin | 2.36a | 3.00 | 2.44 | 2.81 | 0.50 | 0.60 | 0.59 | 0.71 | 0.10 | 0.09 | 1.40 | 1.29 | 1.50 | 1.43 | 0.95 | 0.91 |
Lovastatin was administered at 80 mg/d. Between D1-14, all pigs received a high cholesterol and fat control diet; from D15-29, pigs received either G. lucidum (Gl) extract or lovastatin. The same statistical conclusions were reached if all 10 pigs were compared between D1-14. Pigs were randomly selected to receive either GI or lovastatin before study commencement. Student's, paired, 1-tailed, t-test, was utilized for statistical comparisons. Statistically significant changes (P < 0.05, 1-tailed testing) in cholesterol parameters are indicated as follows: aD1 vs. 14; bD14 vs. 21; cD14 vs. 29. Abbreviations: refer to Table 3. There was a slight trend for 2.5% Gl to reduce LDL/HDL ratio between D14-29 (P < 0.11, 1-tailed testing).