Table 7.
Bile acids | Neutral Sterols | ||||||
Group | NCT | C | CDC | COP-ol | COP-3-one | CHOL erol | CHOL anol |
All pigs (D1) | 1.98 | 0.86 | 0.66a | 2.41a | 0.10a | 1.73a* | 0.96 |
All pigs (D14) | 1.98 | 1.33 | 0.16 | 3.75 | 0.17 | 2.96 | 0.91 |
Gl (D14) | 1.98 | 1.61 | 0.14 | 3.61 | 0.18 | 3.37 | 0.87b* |
Gl (D29) | 1.98 | 0.81 | 0.16 | 4.44 | 0.15 | 3.15 | 1.22 |
Lovastatin (D14) | 1.98 | 0.99 | 0.19 | 3.92 | 0.15 | 2.44 | 0.96 |
Lovastatin (D29) | 1.98 | 1.23 | 0.18 | 3.28 | 0.16 | 2.34 | 1.14 |
Feces were collected on D1, 14 and 29. A quantitative fecal collection was not possible, hence results are expressed per gram of feces. Abbreviations: refer to Table 4, except, NCT, 23- Nor β cholanate 5α,7α,12α triol. A paired, 2-tailed students t-test, equal variances, evaluated effects of the high cholesterol and fat diet, between D1-14 (10 minipigs); and the effects of Gl or lovastatin between D15-29 (5 minipigs/group), indicated as follows: aD1 vs 14, for all minipigs combined (P < 0.001).bD14 vs 29 (P < 0.05). *0.05 < P < 0.1, to indicate statistical trends.