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In vitro clonal copy number heterogeneity can recapitulate heterogeneity found in the original tumor. Comparison of amplifications, deletions, and break points identified on Chromosome 13 (A) and Chromosome 19 (B) in FFPE cores from multiple regions of Tumor 1, and matched cell line LM-MEL-62, derived single cell clones, and independent fresh frozen fragment of Tumor 1.
