Figure 4. Mycobacterium tuberculosis (Mtb) specific T cell responses during antituberculosis treatment in subjects with baseline malnutrition (BMI≤17).

The subgroup of subjects, who started therapy with a BMI≤17 with baseline and week 24 analyzable ELISPOT data (n = 11) are shown. The magnitude of the Mtb specific T cell response is shown by IFN-γ ELISPOT to ESAT-6 and CFP-10 and reported in spot forming units per 250,000 T cells. Connected lines at baseline and week 24 reflect a individual subject's profile for the Mtb specific CD4⁺ T cell response (A) and the Mtb specific CD8⁺ T cell response (B).