Figure 2. a, b, c: Effectiveness of cytokines, TNF-α, IL-6 and IL-10 measurements as markers of disease severity using Receiver operating curve (ROC); d, e, f: Effectiveness of endothelial activation markers, ICAM-1, VCAM-1 and E-selectin as markers of disease severity using Receiver operating curve (ROC).

Solid straight line represents predictive threshold while solid curves line represents the sensitivity and specificity of the respective cytokine and endothelial activation markers. A threshold of 0.5 was used for this study.