Table 2.
Characteristics of the subjects grouped according to glucose tolerance status
|
Characteristics |
NGR (Group I) (n = 1170) |
IGR (Group II) (n = 389) |
DM (Group III) (n = 343) |
P-value |
|||
|---|---|---|---|---|---|---|---|
| All | I vs. II | II vs. III | I vs. III | ||||
| Age (years) |
57.1 ± 8.7 |
57.5 ± 9.1 |
58.1 ± 8.6 |
0.19 |
1.000 |
1.000 |
0.216 |
| BMI (Kg · m-2) |
23.3 ± 3.6 |
24.6 ± 3.5 |
25.2 ± 4.0 |
<0.01 |
<0.001 |
0.120 |
<0.001 |
| WC (cm) |
81.1 ± 9.4 |
84.8 ± 9.2 |
86.8 ± 9.1 |
<0.01 |
<0.001 |
0.011 |
<0.001 |
| SBP (mmHg) |
124 ± 16 |
129 ± 18 |
132 ± 17 |
<0.01 |
<0.001 |
0.017 |
<0.001 |
| DBP (mmHg) |
79 ± 10 |
81 ± 10 |
83 ± 9 |
<0.01 |
0.028 |
0.015 |
<0.001 |
| TC (mmol/L) |
5.17 ± 0.95 |
5.32 ± 0.97 |
5.39 ± 1.00 |
<0.01 |
0.028 |
0.956 |
0.001 |
| TG (mmol · L-1) |
1.45 ± 1.02 |
1.79 ± 1.17 |
2.15 ± 2.04 |
<0.01 |
<0.001 |
<0.001 |
<0.001 |
| HDL-C (mmol · L-1) |
1.44 ± 0.34 |
1.34 ± 0.31 |
1.27 ± 0.29 |
<0.01 |
<0.001 |
0.011 |
<0.001 |
| SCr (umol · L-1) |
66.0 ± 12.7 |
65.5 ± 13.8 |
64.0 ± 14.8 |
0.04 |
1.000 |
0.371 |
0.041 |
| eGFR (ml · min-1 · 1.73 m-2) |
99.4 ± 16.9 |
100.9 ± 18.6 |
105.6 ± 22.4 |
<0.01 |
0.515 |
0.002 |
<0.001 |
| FPG (mmol · L-1) |
5.22 ± 0.45 |
5.85 ± 0.61 |
8.30 ± 2.62 |
<0.01 |
<0.001 |
<0.001 |
<0.001 |
| 2hPG (mmol · L-1) |
5.77 ± 1.11 |
8.15 ± 1.50 |
14.63 ± 5.03 |
<0.01 |
<0.001 |
<0.001 |
<0.001 |
| HbA1c (%) |
5.5 ± 0.4 |
5.7 ± 0.5 |
7.2 ± 1.6 |
<0.01 |
<0.001 |
<0.001 |
<0.001 |
| Hypertension (%) |
462 (39.5) |
212 (54.5) |
231 (65.3) |
<0.01 |
<0.001 |
0.003 |
<0.001 |
| Dyslipidemia (%) |
305 (26.1) |
160 (41.1) |
173 (48.9) |
<0.01 |
<0.001 |
0.033 |
<0.001 |
| CVD (%) |
66 (5.6) |
34 (8.7) |
37 (10.5) |
<0.01 |
0.031 |
0.350 |
0.001 |
| PAD (%) | 38 (3.3) | 19 (4.9) | 15 (4.2) | 0.23 | 0.323 | 0.334 | 0.150 |
Descriptive values are expressed as the mean ± standard deviation or frequency (%). Differences are assessed using the one-way ANOVA test for means and by the chi-square test for proportions. The Bonferroni correction is applied for the multiple testing.
Abbreviations: NGR Normal glucose regulation, IGR Impaired glucose regulation, DM Diabetes mellitus, BMI Body mass index, WC Waist circumstance, SBP Systolic blood pressure, DBP Diastolic blood pressure, PAD Peripheral arterial disease, TC Total cholesterol, TG Triglyceride, HDL High density lipoprotein cholesterol, FPG Fasting plasma glucose, 2hPG 2-hour post-load plasma glucose, HbA1c Glycosylated hemoglobin.