. Author manuscript; available in PMC: 2013 Dec 6.

Published in final edited form as: J Ren Nutr. 2012 Nov 27;23(3):10.1053/j.jrn.2012.08.013. doi: 10.1053/j.jrn.2012.08.013

Table 4.

Association Between Insulin Resistance Indices and Percentage Change of Plasma Amino Acid Concentrations During Repeated Clamp Studies Using a Mixed Model Analysis

Insulin Indices	Plasma Amino Acid Changes
Insulin Indices	Leucine P Values	Phenylalanine P Values	BCAA P Values	TAA P Values
GDR by HECG	.025	.465	.388	.663
LnHOMA-IR	.667	.308	.243	.123
LnHOMA-AD	.054	.885	.850	.584
QUICKI	.538	.406	.286	.141
LnLAR	.245	.959	.610	.900
McAuley's index	.291	.999	.888	.967

BCAA, branched-chain amino acid; GDR, glucose disposal rate; HEGC, hyperinsulinemic euglycemic clamp test; LnHOMA-AD, logarithmic homeostatic model assessment by adiponectin; LnHOMA-IR, logarithmic homeostatic model assessment-insulin resistance; LnLAR, logarithmic leptin to adiponectin ratio; QUICKI, quantitative insulin sensitivity check index; TAA, total amino acid.

Significance of association was tested by a generalized linear mixed model with all 12 patients; repeated measures were included. Logarithmic transformation was performed for HOMA-IR, HOMA-AD, and LAR levels to yield normal distribution before the analysis.