Table 3.
Results for the 8 genes included in the classifier and chosen for qPCR validation on FFPE samples
|
Gene |
Signal log ratio (FTC vs. FTA) |
Non-corrected p-value |
Bonferroni-corrected p-value |
||
|---|---|---|---|---|---|
| Dataset A | Training dataset B | Validation dataset C (FFPE) | Validation dataset C (FFPE) | Validation dataset C (FFPE) | |
|
ELMO1 |
-2.15 |
-2.36 |
-0.98 |
0.0075 |
0.0377 |
|
EMCN |
-1.94 |
-2.25 |
-1.17 |
0.0003 |
0.0015 |
|
ITIH5 |
-1.51 |
-1.98 |
-0.38 |
0.0443 |
0.2214 |
|
KCNAB1 |
-2.45 |
-3.35 |
-1.67 |
0.0020 |
0.0100 |
|
SLCO2A1 |
-1.86 |
-1.45 |
-1.23 |
0.0003 |
0.0014 |
|
LRP1B |
-2.15 |
-2.7 |
Insufficient amplification |
||
|
CA4 |
-2.77 |
-2.92 |
Insufficient amplification |
||
| PLEKHG4B | -1.88 | -1.36 | Insufficient amplification | ||
Log ratios of the 8 genes from microarray training datasets A and B, and validation dataset C (qPCR), are presented. Mann–Whitney U test results for genes validated with qPCR are in bold.