Table 1. Characteristics of 222 premenopausal patients with node-negative breast cancer.

Age, years	Median	47
	Range	30-57
Tumour size, mm	Median	15
	Range	5-45
No. of lymph nodes removed	Median	9
	Range	0-42*
Primary treatment, n	Breast conserving surgery without radiotherapy	57
	Breast conserving surgery + postoperative radiotherapy	106
	Modified radical mastectomy without radiotherapy	52
	Modified radical mastectomy + postoperative radiotherapy	7
Adjuvant medical treatment, n	All	29
	Adjuvant endocrine treatment	8
	Tamoxifen 20 mg daily for 5 years	7
	Oophorectomy	1
	Adjuvant chemotherapy (CMF i.v. nine cycles**)	21
Local/locoregional recurrence *** , No. of patients	≤ 10 years	32
Distant metastases , No. of patients	≤ 10 years	48
DDFS, % (95% CI)	10 years	78 (72-83)
Overall survival, % (95% CI)	10 years	80 (74-84)

^* One patient with axillary exeresis and no identified lymph nodes.

^** CMF, cyclophosphamide, methotrexate, and 5-fluoruracil.

^*** diagnosed as only events, or before distant recurrences