Table 2.
Trait | SNP | Chr | Position | A1 | A2 | χ2 | p Value | Probe ID | Transcript Gene | Transcript Chr | eQTL |
---|---|---|---|---|---|---|---|---|---|---|---|
Glu | rs1335051 | 1 | 107,460,385 | G | T | 9.78 | 1.8 × 10−3 | ILMN_2399463 | VAV3 | 1 | cis |
Glu | rs2303565 | 2 | 219,253,553 | T | C | 9.33 | 2.3 × 10−3 | ILMN_1704985 | CYP27A1 | 2 | cis |
Glu | rs1344642 | 2 | 219,263,506 | G | A | 9.33 | 2.3 × 10−3 | ILMN_1704985 | CYP27A1 | 2 | cis |
Cholesterol | rs11373 | 16 | 55,102,676 | A | G | 17.30 | 3.2 × 10−5 | ILMN_1723116 | AMFR | 16 | cis |
Cholesterol | rs12447395 | 16 | 55,086,841 | T | C | 9.42 | 2.1 × 10−3 | ILMN_1723116 | AMFR | 16 | cis |
Cholesterol | rs2288055 | 16 | 55,059,307 | C | T | 9.25 | 2.4 × 10−3 | ILMN_1723116 | AMFR | 16 | cis |
Cholesterol | rs2288056 | 16 | 55,076,598 | A | G | 9.25 | 2.4 × 10−3 | ILMN_1723116 | AMFR | 16 | cis |
Cholesterol | rs3790113 | 16 | 54,942,221 | T | C | 8.82 | 3.0 × 10−3 | ILMN_1723116 | AMFR | 16 | cis |
HDL | rs3851117 | 11 | 56,993,689 | C | T | 10.13 | 1.5 × 10−3 | ILMN_1765332 | TIMM10 | 11 | cis |
HDL | rs2848630 | 11 | 57,113,483 | G | A | 8.82 | 3.0 × 10−3 | ILMN_1765332 | TIMM10 | 11 | cis |
LDL | rs11373 | 16 | 55,102,676 | A | G | 14.89 | 1.1 × 10−4 | ILMN_1723116 | AMFR | 16 | cis |
Trig | rs927340 | 6 | 2,968,717 | G | A | 10.42 | 1.2 × 10−3 | ILMN_1674285 | LOC401233 | 6 | cis |
Trig | rs17106351 | 14 | 19,762,145 | G | A | 10.21 | 1.4 × 10−3 | ILMN_1719158 | CTBP1 | 4 | trans |
Trig | rs9503375 | 6 | 2,991,536 | T | G | 9.11 | 2.5 × 10−3 | ILMN_1674285 | LOC401233 | 6 | cis |
Trig | rs911536 | 6 | 2,972,130 | G | A | 8.95 | 2.8 × 10−3 | ILMN_1674285 | LOC401233 | 6 | cis |
Weight | rs2243523 | 17 | 78,273,738 | G | T | 13.41 | 2.6 × 10−4 | ILMN_1652333 | FN3KRP | 17 | cis |
BMI | rs2243523 | 17 | 78,273,738 | G | T | 12.95 | 3.2 × 10−4 | ILMN_1652333 | FN3KRP | 17 | cis |
WC | rs10831551 | 11 | 2,194,864 | A | C | 11.75 | 6.1 × 10−4 | ILMN_1668605 | NAAA | 4 | trans |
WC | rs2243523 | 17 | 78,273,738 | G | T | 11.75 | 6.1 × 10−4 | ILMN_1652333 | FN3KRP | 17 | cis |
WC | rs10831570 | 11 | 2,199,188 | C | A | 10.81 | 1.0 × 10−3 | ILMN_1668605 | NAAA | 4 | trans |
Hip | rs2243523 | 17 | 78,273,738 | G | T | 10.62 | 1.5 × 10−3 | ILMN_1652333 | FN3KRP | 17 | cis |
Hip | rs10831551 | 11 | 2,194,864 | A | C | 9.37 | 2.8 × 10−3 | ILMN_1668605 | NAAA | 4 | trans |
WHR | rs2726207 | 4 | 108,858,940 | A | C | 9.55 | 2.0 × 10−3 | ILMN_1781819 | PAPSS1 | 4 | cis |
SBP | rs17526904 | 8 | 29,003,762 | C | T | 12.00 | 7.7 × 10−4 | ILMN_1720059 | HMBOX1 | 8 | cis |
SBP | rs7225515 | 17 | 78,389,072 | G | A | 9.53 | 2.7 × 10−3 | ILMN_1652333 | FN3KRP | 17 | cis |
SBP | rs1044661 | 17 | 78,494,309 | G | A | 9.42 | 2.9 × 10−3 | ILMN_1652333 | FN3KRP | 17 | cis |
DBP | rs4793854 | 17 | 43,927,132 | G | A | 9.31 | 2.3 × 10−3 | ILMN_1810274 | HOXB2 | 17 | cis |
Abbreviations are as follows: A1, allele 1; A2, allele 2; BMI, body mass index; chr, chromosome; DBP, diastolic blood pressure; eQTL, expression quantitative trait locus; glu, plasma glucose; HDL, high-density lipoprotein; hip, hip circumference; LDL, low-density lipoprotein; SBP, systolic blood pressure; trig, triglycerides; WC, waist circumference; and WHR, waist-to-hip ratio.