Table 4.

Overlap of eQTL Genes Mapping to Chromosomal Regions Previously Associated with CVD and Related Traits

eQTL Transcript	eQTL SNP	eQTL p Value	Gene	Chr	Region	PubMed ID	Disease Trait
ILMN_1734830a	rs1476413	1.16 × 10−9	MTHFR	1	1p36.22	19430483; 21909110	blood pressure
ILMN_1746436	rs9263873	9.74 × 10−9	HCG27	6	6p21.33	22319020	coronary heart disease
ILMN_1721113	rs9264904	2.16 × 10−15	HLA-C	6	6p21.33	22319020	coronary heart disease
ILMN_1718063	rs1051338	1.29 × 10−11	LIPA	10	10q23.31	21378988; 21606135	coronary heart disease
ILMN_2400759	rs7313	1.30 × 10−8	CPVL	7	7p14.3	17903298	diabetes related insulin traits
ILMN_1661631	rs103294	4.69 × 10−14	LILRA3	19	19q13.42	20686565	HDL cholesterol
ILMN_1737611	rs2532501	2.02 × 10−8	VAMP1	12	12p13.31	17903296	hip geometry
ILMN_1804735	rs11700748	9.64 × 10−10	CBS	21	21q22.3	20031578	homocysteine levels
ILMN_1734830	rs1476413	1.16 × 10−9	MTHFR	1	1p36.22	20031578	homocysteine levels
ILMN_1795336a	rs7909832	9.63 × 10−14	PTER	10	10p13	19151714	obesity
ILMN_1797375	rs2182667	6.51 × 10−8	KLF12	13	13q22.1	22359512	phospholipid levels (plasma)
ILMN_1722025	rs7736263	1.67 × 10−9	CPEB4	5	5q35.2	20935629	WHR
ILMN_1727045b	rs2835138	1.47 × 10−7	RASGPR3	2	2p22.3	19421330	hypertension

Abbreviations are as follows: chr, chromosome; eQTL, expression quantitative-trait locus; HDL, high-density lipoprotein; and WHR, waist-to-hip ratio.

^aThese eQTLs are also reported in Garnier et al.⁶⁴

^btrans-acting eQTL-SNP cluster on chromosome 21.